HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanone → 3-(5-Chloro-thiazol-2-yl)-1-cyclohex-3-enyl-1-cyclohexyl-urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | 2-Amino-5-chlorothiazole | HCID 38942 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Cyclohex-3-en-1-amine | HCID 13040867 | — |
| Product | 3-(5-Chloro-thiazol-2-yl)-1-cyclohex-3-enyl-1-cyclohexyl-urea | HCID 57883652 | — |
| Product | Cyclohex-3-enyl-cyclohexylamine | HCID 65702898 | — |
Reaction Steps
Cyclohex-3-enyl-cyclohexylamine was prepared by reductive amination of cyclohex-3-enylamine and cyclohexanone using general procedure (B). Reaction with CDI and 5-chloro-2-aminothiazole using general procedure (A) gave the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263634B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-e23f8a033f6b46bfa7cff55e3a2314c8 |
| Source note | uspto-grants-2012_09 |