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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384302Generated: October 31, 2026

4-Morpholinecarbonyl chloride → HCID 86611232, compound

https://huagongshe.com/reaction/2384302

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Morpholinecarbonyl chlorideHCID 84810—
ReactantHCID 178472291HCID 178472291—
ProductHCID 86611232HCID 86611232—
ProductHCID 178461382HCID 178461382—

Reaction Steps

3-(2-{3-(4-Methyl-cyclohexyl)-3-[1-(morpholine-4-carbonyl)-piperidin-4-yl]-ureido}-thiazol-5-ylsulfanyl)-propionic acid ethyl ester was prepared in a similar manner to Example 554 using 3-{2-[3-(trans-4-methyl-cyclohexyl)-3-piperidin-4-yl-ureido]-thiazol-5-ylsulfanyl}-propionic acid ethyl ester and 4-morpholinecarbonyl chloride. Hydrolysis using general procedure (F) gave the title compound

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263634B2
Source datasetuspto-grants-2012_09
ORD IDord-13aca0cc556c432e9832cd7cf17aef28
Source noteuspto-grants-2012_09