5-Bromosalicylic acid → 5-Bromo-N-[4,5-bis(furan-2-yl)oxazol-2-yl]-2-hydroxybenzamide

HRID 2384336Notes

Reaction equation

HRID 2384336 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[O:14][C:15]([C:23]2[O:24][CH:25]=[CH:26][CH:27]=2)=[C:16]([C:18]2[O:19][CH:20]=[CH:21][CH:22]=2)[N:17]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[O:14][C:15]([C:23]2[O:24][CH:25]=[CH:26][CH:27]=2)=[C:16]([C:18]2[O:19][CH:20]=[CH:21][CH:22]=2)[N:17]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 126152352-Amino-4,5-bis(furan-2-yl)oxazole

Product 1

HCID 100018725-Bromo-N-[4,5-bis(furan-2-yl)oxazol-2-yl]-2-hydroxybenzamideYield 12.9%

Procedure

Using 5-bromosalicylic acid and 2-amino-4,5-bis(furan-2-yl)oxazole as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-8199b27aadf84d0287828abecf0df158
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

Loading…