5-Bromosalicylic acid → HCID 10044517, compound

HRID 2384337Notes

Reaction equation

HRID 2384337 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[NH2:12][C:13]1[S:14][C:15]([C:18]([F:21])([F:20])[F:19])=[N:16][N:17]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:12][C:13]1[S:14][C:15]([C:18]([F:21])([F:20])[F:19])=[N:16][N:17]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 826341,3,4-Thiadiazol-2-amine, 5-(trifluoromethyl)-

Product 1

HCID 10044517HCID 10044517, compoundYield 80.2%

Procedure

Using 5-bromosalicylic acid and 2-amino-5-(trifluoromethyl)-1,3,4-thiadiazole as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-19a59145cd0048309b2aebd5d88be6a3
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

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