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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384347Generated: October 25, 2026

5-Methylsalicylic acid → N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-methyl-benzamide

https://huagongshe.com/reaction/2384347

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methylsalicylic acidHCID 6973—
ReactantBenzenamine, 3,5-bis(trifluoromethyl)-HCID 9480—
ProductN-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-methyl-benzamideHCID 1121068154.9%

Reaction Steps

Using 5-methylsalicylic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-eabbc62894ae4d50a40a5ef4a9487754
Source noteuspto-grants-2012_09