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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384359Generated: October 30, 2026

Phenylacetylene → N-[3,5-Bis(trifluoromethyl)phenyl]-2-hydroxy-5-(phenylethynyl)-benzamide

https://huagongshe.com/reaction/2384359

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylacetyleneHCID 10821—
ReactantN-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-iodo-benzamideHCID 11190699—
ProductN-[3,5-Bis(trifluoromethyl)phenyl]-2-hydroxy-5-(phenylethynyl)-benzamideHCID 11430827—

Reaction Steps

Using N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-iodobenzamide and phenylacetylene as the raw materials, the same operation as the example 66 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-26971e2b707848c9b6d4941f6502925c
Source noteuspto-grants-2012_09