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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384361Generated: November 1, 2026

Benzenamine, 3,5-bis(trifluoromethyl)- → N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-(trifluoromethyl)benzamide

https://huagongshe.com/reaction/2384361

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenamine, 3,5-bis(trifluoromethyl)-HCID 9480—
Reactant2-hydroxy-5-(trifluoromethyl)benzoic AcidHCID 11117203—
ProductN-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-5-(trifluoromethyl)benzamideHCID 11212219—

Reaction Steps

Using 2-hydroxy-5-(trifluoromethyl)benzoic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound. (2-Hydroxy-5-(trifluoromethyl)benzoic acid: refer to Chem. Pharm. Bull., 1996, 44, 734.)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-6df3c672d7bf47f2969d626db5cb5728
Source noteuspto-grants-2012_09