化工社化工社 化学情報印刷レポート · 研究参考用
Benzenamine, 3,5-bis(trifluoromethyl)- → N1,N3-Bis[3,5-bis(trifluoromethyl)phenyl]-4-hydroxyisophthalamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzenamine, 3,5-bis(trifluoromethyl)- | HCID 9480 | — |
| 反応物 | 4-Hydroxyisophthalic acid | HCID 12490 | — |
| 反応物 | Phosphorus trichloride | HCID 24387 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | N1,N3-Bis[3,5-bis(trifluoromethyl)phenyl]-4-hydroxyisophthalamide | HCID 86595535 | 25% |
反応手順
Using 4-hydroxyisophthalic acid (182 mg, 1 mmol), 3,5-bis(trifluoromethyl)-aniline (687 mg, 3 mmol), phosphorus trichloride (87 μl; 1 mmol) and toluene (10 mL), the same operation as the example 16 gave the title compound (151 mg, 25.0%) as a white crystal.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08263657B2 |
| 出典データセット | uspto-grants-2012_09 |
| ORD ID | ord-fb88613fc275460d97c2c39f4f9ce388 |
| 出典メモ | uspto-grants-2012_09 |