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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384381Generated: October 27, 2026

Piperidine → 2-Benzyloxy-N-[3,5-bis(trifluoromethyl)phenyl]-5-(piperidine-1-carbonyl)benzamide

https://huagongshe.com/reaction/2384381

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant4-benzyl-N-[3,5-bis(trifluoromethyl)phenyl]isophthalamic acidHCID 86595538—
Product2-Benzyloxy-N-[3,5-bis(trifluoromethyl)phenyl]-5-(piperidine-1-carbonyl)benzamideHCID 1786016556.4%

Reaction Steps

Using 4-benzyl-N-[3,5-bis(trifluoromethyl)phenyl]isophthalamic acid and piperidine as the raw materials, the same operation as the example 84(3) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-581b49899e42459098078922fa35abdd
Source noteuspto-grants-2012_09