Benzenamine, 3,5-bis(trifluoromethyl)- → HCID 10340450, compound

HRID 2384384Notes

Reaction equation

HRID 2384384 reaction equation
[CH3:1][N:2]([CH3:13])[C:3]1[CH:11]=[C:7]([C:8]([OH:10])=O)[C:6]([OH:12])=[CH:5][CH:4]=1.[F:14][C:15]([F:28])([F:27])[C:16]1[CH:17]=[C:18]([CH:20]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:22]=1)[NH2:19]>>[F:14][C:15]([F:27])([F:28])[C:16]1[CH:17]=[C:18]([NH:19][C:8](=[O:10])[C:7]2[CH:11]=[C:3]([N:2]([CH3:1])[CH3:13])[CH:4]=[CH:5][C:6]=2[OH:12])[CH:20]=[C:21]([C:23]([F:24])([F:26])[F:25])[CH:22]=1

Participants

3

Reactant 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 17860272HCID 17860272, compound

Product 1

HCID 10340450HCID 10340450, compoundYield 28.8%

Procedure

Using 5-dimethylaminosalicylic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-85da748c2812479cbfba8eaeb7222405
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

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