Benzenamine, 3,5-bis(trifluoromethyl)- → HCID 23070355, compound

HRID 2384391Notes

Reaction equation

HRID 2384391 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([OH:11])[C:5](=[CH:9][CH:10]=1)[C:6]([OH:8])=O.[F:12][C:13]([F:26])([F:25])[C:14]1[CH:15]=[C:16]([CH:18]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:20]=1)[NH2:17]>>[F:12][C:13]([F:25])([F:26])[C:14]1[CH:15]=[C:16]([NH:17][C:6](=[O:8])[C:5]2[CH:9]=[CH:10][C:2]([Cl:1])=[CH:3][C:4]=2[OH:11])[CH:18]=[C:19]([C:21]([F:22])([F:24])[F:23])[CH:20]=1

Participants

3

Reactant 2

HCID 9480Benzenamine, 3,5-bis(trifluoromethyl)-HCID 787824-Chlorosalicylic acid

Product 1

HCID 23070355HCID 23070355, compoundYield 55.8%

Procedure

Using 4-chlorosalicylic acid and 3,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-a3bd4d315a9e4f06907ebcdab9bf0252
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

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