5-Chlorosalicylic Acid → HCID 17860294, compound

HRID 2384392Notes

Reaction equation

HRID 2384392 reaction equation
[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[F:12][C:13]([F:27])([F:26])[C:14]1[C:15]([Br:25])=[C:16]([CH:18]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:20]=1)[NH2:17]>>[F:26][C:13]([F:12])([F:27])[C:14]1[C:15]([Br:25])=[C:16]([NH:17][C:7](=[O:9])[C:6]2[CH:10]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=2[OH:11])[CH:18]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:20]=1

Participants

3

Reactant 2

HCID 94475-Chlorosalicylic AcidHCID 43054482-Bromo-3,5-bis(trifluoromethyl)aniline

Product 1

HCID 17860294HCID 17860294, compoundYield 14.5%

Procedure

Using 5-chlorosalicylic acid and 3,5-bis(trifluoromethyl)-2-bromoaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-343a8ee6c6eb4e6f929e136740860f6c
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

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