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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384395Generated: November 3, 2026

5-Methylsalicylic acid → N-[2,5-Bis(trifluoromethyl)phenyl]-2-hydroxy-5-methylbenzamide

https://huagongshe.com/reaction/2384395

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methylsalicylic acidHCID 6973—
Reactant2,5-Bis(trifluoromethyl)anilineHCID 719818—
ProductN-[2,5-Bis(trifluoromethyl)phenyl]-2-hydroxy-5-methylbenzamideHCID 590148201.5%

Reaction Steps

Using 5-methylsalicylic acid and 2,5-bis(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-6dac18ef84764fdb98e97ee4f53b30ae
Source noteuspto-grants-2012_09