5-Bromosalicylic acid → HCID 24285168, compound

HRID 2384399Notes

Reaction equation

HRID 2384399 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[F:12][C:13]([F:22])([F:21])[C:14]1[CH:15]=[C:16]([CH:18]=[CH:19][CH:20]=1)[NH2:17]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:17][C:16]1[CH:18]=[CH:19][CH:20]=[C:14]([C:13]([F:12])([F:21])[F:22])[CH:15]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 73753-(Trifluoromethyl)aniline

Product 1

HCID 24285168HCID 24285168, compoundYield 50.3%

Procedure

Using 5-bromosalicylic acid and 3-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-464542e8eff74580927c0138a041ff62
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

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