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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 238441Generated: October 30, 2026

1-Tert-butyl 4-ethyl piperidine-1,4-dicarboxylate → Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/238441

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Tert-butyl 4-ethyl piperidine-1,4-dicarboxylateHCID 2758812—
Reactant2-morpholin-4-ylpropan-1-olHCID 10986371—
ProductTert-butyl 4-(hydroxymethyl)piperidine-1-carboxylateHCID 2764081—

Reaction Steps

1-Boc-4-Hydroxymethyl-piperidine was prepared from 1-Boc-piperidine-4-carboxylic acid ethyl ester by a procedure similar to that described in the preparation of 2-morpholin-4-yl-propanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642624B2
Source datasetuspto-grants-2014_02
ORD IDord-2e4469cfadd9407c8f5e1dae06f47ea4
Source noteuspto-grants-2014_02