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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384418Generated: October 25, 2026

5-Bromosalicylic acid → 5-Bromo-2-hydroxy-N-[2-morpholino-5-(trifluoromethyl)phenyl]-benzamide

https://huagongshe.com/reaction/2384418

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromosalicylic acidHCID 6972—
ReactantN-(2-Amino-4-(trifluoromethyl)phenyl)morpholineHCID 136624—
Product5-Bromo-2-hydroxy-N-[2-morpholino-5-(trifluoromethyl)phenyl]-benzamideHCID 1007218265.9%

Reaction Steps

Using 5-bromosalicylic acid and 2-morpholino-5-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-7775fae0f67e4a67b8fd2c249943e39b
Source noteuspto-grants-2012_09