5-Chlorosalicylic Acid → HCID 5274059, compound

HRID 2384419Notes

Reaction equation

HRID 2384419 reaction equation
[Cl:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[F:12][C:13]([F:22])([F:21])[C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[CH:16][CH:15]=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:18][C:17]1[CH:19]=[CH:20][C:14]([C:13]([F:12])([F:21])[F:22])=[CH:15][CH:16]=1)=[O:9]

Participants

3

Reactant 2

HCID 94475-Chlorosalicylic AcidHCID 99644-(Trifluoromethyl)aniline

Product 1

HCID 5274059HCID 5274059, compoundYield 75%

Procedure

Using 5-chlorosalicylic acid and 4-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-32d26e21a7d54f12bc2db574383bb1fc
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

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