5-Methylsalicylic acid → HCID 17860175, compound

HRID 2384422Notes

Reaction equation

HRID 2384422 reaction equation
[CH3:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:14]=1[NH2:15]>>[Cl:12][C:13]1[CH:19]=[CH:18][C:17]([C:20]([F:22])([F:23])[F:21])=[CH:16][C:14]=1[NH:15][C:7](=[O:9])[C:6]1[CH:10]=[C:2]([CH3:1])[CH:3]=[CH:4][C:5]=1[OH:11]

Participants

3

Reactant 2

HCID 69735-Methylsalicylic acidHCID 8475Benzenamine, 2-chloro-5-(trifluoromethyl)-

Product 1

HCID 17860175HCID 17860175, compoundYield 15.8%

Procedure

Using 5-methylsalicylic acid and 2-chloro-5-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-eeb13a2adf7846e09db14b452c869ff4
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

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