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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384424Generated: October 26, 2026

5-Methylsalicylic acid → N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-hydroxy-5-methylbenzamide

https://huagongshe.com/reaction/2384424

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methylsalicylic acidHCID 6973—
Reactant4-Chloro-3-(trifluoromethyl)anilineHCID 67574—
ProductN-[4-Chloro-3-(trifluoromethyl)phenyl]-2-hydroxy-5-methylbenzamideHCID 6665720370.4%

Reaction Steps

Using 5-methylsalicylic acid and 4-chloro-3-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-37060c32ae2845298780cc3e2a8021a2
Source noteuspto-grants-2012_09