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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384425Generated: October 25, 2026

5-Methylsalicylic acid → 2-Hydroxy-5 methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]benzamide

https://huagongshe.com/reaction/2384425

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methylsalicylic acidHCID 6973—
Reactant4-Methyl-3-(trifluoromethyl)anilineHCID 2737715—
Product2-Hydroxy-5 methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]benzamideHCID 1786025363.7%

Reaction Steps

Using 5-methylsalicylic acid and 4-methyl-3-(trifluoromethyl)aniline as the raw materials, the same operation as the example 16 gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-1bf8a67346ff41d699cdb22bcf56784e
Source noteuspto-grants-2012_09