5-Bromosalicylic acid → HCID 487714, compound

HRID 2384430Notes

Reaction equation

[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][CH:19]=1)[NH2:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:16][C:15]1[CH:17]=[CH:18][CH:19]=[C:13]([Cl:12])[CH:14]=1)=[O:9]

Participants

Reactant 2

HCID 69725-Bromosalicylic acid

HCID 79323-Chloroaniline

Product 1

HCID 487714HCID 487714, compoundYield 63.1%

Procedure

Using 5-bromosalicylic acid and 3-chloroaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record: ord-c5ee88d7a19a4ed1a8c8a1f43dc0ba31
Source dataset: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08263657B2

Reaction notes

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