5-Bromosalicylic acid → HCID 17860206, compound

HRID 2384433Notes

Reaction equation

HRID 2384433 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[F:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([F:20])[CH:19]=1)[NH2:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:16][C:15]1[CH:14]=[C:13]([F:12])[CH:19]=[C:18]([F:20])[CH:17]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 965953,5-Difluoroaniline

Product 1

HCID 17860206HCID 17860206, compoundYield 36.3%

Procedure

Using 5-bromosalicylic acid and 3,5-difluoroaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-566d2a010b7e4f908f730e1acc1f7cf8
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

Loading…