5-Iodosalicylic acid → N-(3,5-Dichlorophenyl)-2-hydroxy-5-iodobenzamide

HRID 2384437Notes

Reaction equation

HRID 2384437 reaction equation
[I:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([Cl:20])[CH:19]=1)[NH2:16]>>[Cl:12][C:13]1[CH:14]=[C:15]([NH:16][C:7](=[O:9])[C:6]2[CH:10]=[C:2]([I:1])[CH:3]=[CH:4][C:5]=2[OH:11])[CH:17]=[C:18]([Cl:20])[CH:19]=1

Participants

3

Reactant 2

HCID 83885-Iodosalicylic acidHCID 122813,5-Dichloroaniline

Product 1

HCID 17860295N-(3,5-Dichlorophenyl)-2-hydroxy-5-iodobenzamideYield 65.4%

Procedure

Using 5-iodosalicylic acid and 3,5-dichloroaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-d3388bf0ace34fde93df6015a05368a2
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

Loading…