5-Bromosalicylic acid → 5-Bromo-2-hydroxy-N-(3,4,5-trichlorophenyl)benzamide

HRID 2384442Notes

Reaction equation

HRID 2384442 reaction equation
[Br:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=O)[C:5]([OH:11])=[CH:4][CH:3]=1.[Cl:12][C:13]1[CH:14]=[C:15]([CH:17]=[C:18]([Cl:21])[C:19]=1[Cl:20])[NH2:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([CH:10]=1)[C:7]([NH:16][C:15]1[CH:14]=[C:13]([Cl:12])[C:19]([Cl:20])=[C:18]([Cl:21])[CH:17]=1)=[O:9]

Participants

3

Reactant 2

HCID 69725-Bromosalicylic acidHCID 124693,4,5-Trichloroaniline

Product 1

HCID 178603255-Bromo-2-hydroxy-N-(3,4,5-trichlorophenyl)benzamideYield 78.6%

Procedure

Using 5-bromosalicylic acid and 3,4,5-trichloroaniline as the raw materials, the same operation as the example 16 gave the title compound.

Sources & evidence

ORD record
ord-c086ff0fbb1b4f76a161dba8d89d729b
Source dataset
uspto-grants-2012_09
Patent number
US08263657B2

Reaction notes

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