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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384464Generated: October 30, 2026

5-Bromosalicylic acid → 5-Bromo-N-[5-bromo-4-(trifluoromethyl)thiazol-2-yl]-2-hydroxybenzamide

https://huagongshe.com/reaction/2384464

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromosalicylic acidHCID 6972—
Reactant5-Bromo-4-(trifluoromethyl)-1,3-thiazol-2-amineHCID 15710701—
Product5-Bromo-N-[5-bromo-4-(trifluoromethyl)thiazol-2-yl]-2-hydroxybenzamideHCID 10049198—

Reaction Steps

Using 5-bromosalicylic acid and 2-amino-5-bromo-4-(trifluoromethyl)thiazole as the raw materials, the same operation as the example 16 gave the title compound. (2-Amino-5-bromo-4-(trifluoromethyl)thiazole: refer to J. Heterocycl. Chem., 1991, 28, 1017.)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-75bedeb2e7ee4a6587c729efd9d41b95
Source noteuspto-grants-2012_09