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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384478Generated: October 27, 2026

5-Chlorosalicylic Acid → 2-(5-Chloro-2-hydroxybenzoyl)amino-4-phenylthiazole-5-carboxylic acid ethyl ester

https://huagongshe.com/reaction/2384478

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chlorosalicylic AcidHCID 9447—
ReactantEthyl 2-amino-4-phenyl-1,3-thiazole-5-carboxylateHCID 73239—
Product2-(5-Chloro-2-hydroxybenzoyl)amino-4-phenylthiazole-5-carboxylic acid ethyl esterHCID 8659554269.4%

Reaction Steps

Using 5-chlorosalicylic acid and 2-amino-4-phenylthiazole-5-carboxylic acid ethyl ester as the raw materials, the same operation as the example 195(3) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-b86c61f6611c43deb8d84a183a3ee3f7
Source noteuspto-grants-2012_09