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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384483Generated: October 26, 2026

5-Bromosalicylic acid → 2-(5-Bromo-2-hydroxybenzoyl)amino 4-(trifluoromethyl)thiazole-5-carboxylic acid ethyl ester

https://huagongshe.com/reaction/2384483

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromosalicylic acidHCID 6972—
Reactant5-Thiazolecarboxylic acid, 2-amino-4-(trifluoromethyl)-, ethyl esterHCID 67656—
Product2-(5-Bromo-2-hydroxybenzoyl)amino 4-(trifluoromethyl)thiazole-5-carboxylic acid ethyl esterHCID 8659554488.7%

Reaction Steps

Using 5-bromosalicylic acid and 2-amino-4-(trifluoromethyl)thiazole-5-carboxylic acid ethyl ester as the raw materials, the same operation as the example 195(3) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263657B2
Source datasetuspto-grants-2012_09
ORD IDord-08c97dcd246849a39a303313179dd43c
Source noteuspto-grants-2012_09