Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 238449Generated: October 26, 2026

1-(2-Chloroethyl)piperidine → 1-[2-(5-Nitro-2-pentafluoroethyl-phenoxy)-ethyl]-piperidine

https://huagongshe.com/reaction/238449

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Chloroethyl)piperidineHCID 74827—
ReactantPhenol, 5-nitro-2-(1,1,2,2,2-pentafluoroethyl)-HCID 17756181—
Reactant1-[2-(2-Tert-butyl-5-nitro-phenoxy)-ethyl]-piperidineHCID 21959506—
Product1-[2-(5-Nitro-2-pentafluoroethyl-phenoxy)-ethyl]-piperidineHCID 21959346—

Reaction Steps

1-[2-(5-Nitro-2-pentafluoroethyl-phenoxy)-ethyl]-piperidine was prepared from 5-nitro-2-pentafluoroethylphenol and 1-(2-chloroethyl)piperidine by a procedure similar to that described in the preparation of 1-[2-(2-tert-butyl-5-nitro-phenoxy)-ethyl]-piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642624B2
Source datasetuspto-grants-2014_02
ORD IDord-cfa85a54d05a4937ae74089b19c25afa
Source noteuspto-grants-2014_02