HCID 68504344, compound → HCID 16202505, compound

Participants

Reaction Conditions

Reaction Steps

89.0 g (0.28 mol) of N-(4-fluoro-3-nitrobenzoyl)-N′-isopropyl-N′-methylsulfamide in methanol were admixed with 5.9 g (10 mol %) of Pd/C and hydrogenated with 2-5 bar of hydrogen with stirring at 25-30° C. After 12 h the solution was depressurized, the reaction mixture was filtered and the solvent was removed by distillation. This gave 80.1 g (98%) of the title compound in the form of a beige solid (m.p.: 148-150° C.).

Provenance & Evidence