HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Hydroxyproline → HCID 67242937, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Hydroxyproline | HCID 5810 | — |
| Reactant | 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one | HCID 67240096 | — |
| Product | HCID 67242937 | HCID 67242937 | — |
Reaction Steps
1-{5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-4-(R)-hydroxy-pyrrolidine-2-(S)-carboxylic acid was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one and 4-(R)-hydroxy-pyrrolidine-2-(S)-carboxylic acid following General Procedure C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263781B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-9e88a923f0a24c74923b51d3807407be |
| Source note | uspto-grants-2012_09 |