2-Bromo-1-(bromomethyl)-4-(trifluoromethyl)benzene → 1-(2-Bromo-4-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

HRID 2384632Notes

Reaction equation

HRID 2384632 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[N:2]1.[Br:12][C:13]1[CH:18]=[C:17]([C:19]([F:22])([F:21])[F:20])[CH:16]=[CH:15][C:14]=1[CH2:23]Br>>[Br:12][C:13]1[CH:18]=[C:17]([C:19]([F:20])([F:21])[F:22])[CH:16]=[CH:15][C:14]=1[CH2:23][N:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 149499362-Bromo-1-(bromomethyl)-4-(trifluoromethyl)benzeneHCID 212506441H-Indazole-5-carboxaldehyde

Product 1

HCID 866545541-(2-Bromo-4-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

Procedure

1-(2-Bromo-4-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde was prepared from 1H-indazole-5-carbaldehyde and 2-bromo-1-bromomethyl-4-trifluoromethyl-benzene following General Procedure A.

Sources & evidence

ORD record
ord-e66614a401114b7d996aa3967bcae572
Source dataset
uspto-grants-2012_09
Patent number
US08263781B2

Reaction notes

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