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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384641Generated: October 30, 2026

(-)-Nipecotic acid → HCID 86654556, compound

https://huagongshe.com/reaction/2384641

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(-)-Nipecotic acidHCID 1796510—
Reactant5-[1-(2,4-bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]2-methylsulfanyl-thiazol-4-oneHCID 86654543—
ProductHCID 86654556HCID 86654556—

Reaction Steps

1-{5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-piperidine-3-(R)-carboxylic acid was prepared from 5-[1-(2,4-bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one and piperidine-3-(R)-carboxylic acid following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263781B2
Source datasetuspto-grants-2012_09
ORD IDord-fd28292861cf49f9a2af7499e39f0030
Source noteuspto-grants-2012_09