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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384647Generated: November 1, 2026

D-Proline → HCID 67239874, compound

https://huagongshe.com/reaction/2384647

Reaction equation

Participants

RoleNameHCIDCharge
ReactantD-ProlineHCID 8988—
Reactant5-[1-(4-methoxy-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-oneHCID 67240657—
ProductHCID 67239874HCID 67239874—

Reaction Steps

1-{5-[1-(4-Methoxy-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-pyrrolidine-2-(R)-carboxylic acid was prepared from 5-[1-(4-methoxy-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one and pyrrolidine-2-(R)-carboxylic acid following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263781B2
Source datasetuspto-grants-2012_09
ORD IDord-d1256519d0bb49e18257cad557e24d3e
Source noteuspto-grants-2012_09