HCID 18452962, compound → HCID 67241959, compound

HRID 2384725Notes

Reaction equation

HRID 2384725 reaction equation
[Cl:1][C:2]1[CH:28]=[CH:27][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([CH:16]=[C:17]4[S:21][C:20](SCCC)=[N:19][C:18]4=[O:26])=[CH:13][CH:14]=3)[CH:9]=[N:8]2)=[C:4]([C:29]([F:32])([F:31])[F:30])[CH:3]=1.[C:33]1(=[O:41])[CH:37]2[CH2:38][NH:39][CH2:40][CH:36]2[CH2:35][O:34]1>>[Cl:1][C:2]1[CH:28]=[CH:27][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([CH:16]=[C:17]4[S:21][C:20]([N:39]5[CH2:40][CH:36]6[CH2:35][O:34][C:33](=[O:41])[CH:37]6[CH2:38]5)=[N:19][C:18]4=[O:26])=[CH:13][CH:14]=3)[CH:9]=[N:8]2)=[C:4]([C:29]([F:30])([F:32])[F:31])[CH:3]=1

Participants

3

Reactant 2

HCID 18452962HCID 18452962, compoundHCID 672409345-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-propylsulfanyl-thiazol-4-one

Product 1

HCID 67241959HCID 67241959, compound

Procedure

5-{5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-hexahydro-furo[3,4-c]pyrrol-1-one was prepared from 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-propylsulfanyl-thiazol-4-one and hexahydro-furo[3,4-c]pyrrol-1-one following General Procedure B.

Sources & evidence

ORD record
ord-280d51e8e09642ef8c311167a45d19f3
Source dataset
uspto-grants-2012_09
Patent number
US08263781B2

Reaction notes

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