HuagongsheHuagongshe Chemistry Print Report · For research reference only
[1,4'-Bipiperidin]-3-ol → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(3-hydroxy-[1,4']bipiperidinyl-1'-yl)-thiazol-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [1,4'-Bipiperidin]-3-ol | HCID 21091574 | — |
| Reactant | 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-propylsulfanyl-thiazol-4-one | HCID 67240934 | — |
| Product | 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(3-hydroxy-[1,4']bipiperidinyl-1'-yl)-thiazol-4-one | HCID 67239637 | — |
Reaction Steps
5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(3-hydroxy-[1,4′]bipiperidinyl-1′-yl)-thiazol-4-one was prepared from 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-propylsulfanyl-thiazol-4-one and [1,4′]Bipiperidinyl-3-ol following General Procedure B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263781B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-e7bc64f494a1437eaea375613d68bad0 |
| Source note | uspto-grants-2012_09 |