2-(Methylsulfanyl)-4,5-dihydro-1,3-thiazol-4-one → 2-(2-Hydroxymethyl-morpholin-4-yl)-thiazol-4-one

HRID 2384758Notes

Reaction equation

HRID 2384758 reaction equation
CS[C:3]1[S:4][CH2:5][C:6](=[O:8])[N:7]=1.[NH:9]1[CH2:14][CH2:13][O:12][CH:11]([CH2:15][OH:16])[CH2:10]1>>[OH:16][CH2:15][CH:11]1[O:12][CH2:13][CH2:14][N:9]([C:3]2[S:4][CH2:5][C:6](=[O:8])[N:7]=2)[CH2:10]1

Participants

3

Reactant 2

HCID 14820222-(Methylsulfanyl)-4,5-dihydro-1,3-thiazol-4-oneHCID 3497988Morpholin-2-ylmethanol

Product 1

HCID 672406862-(2-Hydroxymethyl-morpholin-4-yl)-thiazol-4-one

Procedure

2-(2-Hydroxymethyl-morpholin-4-yl)-thiazol-4-one was prepared from 2-Methylsulfanyl-thiazol-4-one and Morpholin-2-yl-methanol following general procedure E.

Sources & evidence

ORD record
ord-4e43a18ddf3f4f2987cbadd4e375aba3
Source dataset
uspto-grants-2012_09
Patent number
US08263781B2

Reaction notes

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