HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Proline, 4-fluoro-, cis- → HCID 67239864, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Proline, 4-fluoro-, cis- | HCID 10057550 | — |
| Reactant | 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one | HCID 67240123 | — |
| Product | HCID 67239864 | HCID 67239864 | — |
Reaction Steps
1-[5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]-4-(S)-fluoro-L-proline was prepared from 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 4-(S)—Fluoro-pyrrolidine-2-(S)-carboxylic acid following General Procedure C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263781B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-0f52f779115f4a3cab4561b467a51fea |
| Source note | uspto-grants-2012_09 |