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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384785Generated: October 31, 2026

Piperazine, 1,3-dimethyl-, (3R)-rel- → HCID 67240937, compound

https://huagongshe.com/reaction/2384785

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazine, 1,3-dimethyl-, (3R)-rel-HCID 59768148—
Reactant5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-oneHCID 67240123—
ProductHCID 67240937HCID 67240937—

Reaction Steps

5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2-(2(R),4-dimethylpiperazin-1-yl)-1,3-thiazol-4(5H)-one was prepared from 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 1,3-(R)-Dimethyl-piperazine following general procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263781B2
Source datasetuspto-grants-2012_09
ORD IDord-817973d856b6412089cf4be97bd0d9fe
Source noteuspto-grants-2012_09