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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384796Generated: November 1, 2026

rel-(2R,6S)-4-(3-Azetidinyl)-2,6-dimethylmorpholine → HCID 67240575, compound

https://huagongshe.com/reaction/2384796

Reaction equation

Participants

RoleNameHCIDCharge
Reactantrel-(2R,6S)-4-(3-Azetidinyl)-2,6-dimethylmorpholineHCID 66592027—
Reactant5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-oneHCID 67240123—
ProductHCID 67240575HCID 67240575—

Reaction Steps

5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2-[3-(2,6-cis-dimethylmorpholin-4-yl)azetidin-1-yl]-1,3-thiazol-4(5H)-one was prepared from 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 4-Azetidin-3-yl-2,6-(cis)-dimethyl-morpholine following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263781B2
Source datasetuspto-grants-2012_09
ORD IDord-954ad8214ef14d10afc850bd6f010c62
Source noteuspto-grants-2012_09