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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384805Generated: November 2, 2026

Cyclopropanecarbonyl chloride → HCID 86654608, compound

https://huagongshe.com/reaction/2384805

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarbonyl chlorideHCID 77637—
ReactantHCID 86654601HCID 86654601—
ProductHCID 86654608HCID 86654608—

Reaction Steps

5-({1-[2,4-Bis(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2-[4-(cyclopropylcarbonyl)-3-(R)-(hydroxymethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one was prepared from 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(3-(R)-hydroxymethyl-piperazin-1-yl)-thiazol-4-one (example 139) and Cyclopropanecarbonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263781B2
Source datasetuspto-grants-2012_09
ORD IDord-a8ff7ce996db4de895f468e104f1ea38
Source noteuspto-grants-2012_09