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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384856Generated: November 1, 2026

2-(Chloromethyl)-3-(trifluoromethyl)pyridine → 1-(3-Trifluoromethyl-pyridin-2-ylmethyl)-1H-indazole-5-carbaldehyde

https://huagongshe.com/reaction/2384856

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)-3-(trifluoromethyl)pyridineHCID 18361737—
Reactant1H-Indazole-5-carboxaldehydeHCID 21250644—
Product1-(3-Trifluoromethyl-pyridin-2-ylmethyl)-1H-indazole-5-carbaldehydeHCID 86654628—

Reaction Steps

1-(3-Trifluoromethyl-pyridin-2-ylmethyl)-1H-indazole-5-carbaldehyde was prepared from 1H-Indazole-5-carbaldehyde and 2-Chloromethyl-3-trifluoromethyl-pyridine following General Procedure A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263781B2
Source datasetuspto-grants-2012_09
ORD IDord-97cbfc1fdc6d467c8a3cbc6ebcf557e4
Source noteuspto-grants-2012_09