HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-[4-(Azetidin-3-yloxy)-3-methoxy-phenyl]-2-(4-chloro-phenyl)-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-[4-(azetidin-3-yloxy)-3-methoxy-phenyl]-2-(4-chloro-phenyl)-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one | HCID 68951090 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 6-[4-(Azetidin-3-yloxy)-3-methoxy-phenyl]-2-(4-chloro-phenyl)-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one hydrochloride | HCID 68951089 | — |
Reaction Steps
Prepare the HCl salt by dissolving the residue in CH2Cl2 and adding HCl in ethanol. Add ether to the mixture then filter and dry the solid to obtain the title compound. LC-MS/ES m/z (35Cl) 441.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263772B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-9b44716eb4e94ac98a92731479aba650 |
| Source note | uspto-grants-2012_09 |