反应详情

1-(1-Methyl(4-piperidyl))-6-nitroindoline (3 g, Step A) was dissolved in 100 mL MeOH, and the mixture was bubbled with N2 for 10 min. 10% Pd/C (200 mg) was added and the mixture was stirred under H2 overnight. The mixture was filtered through Celite® and concentrated in vacuo to afford a light yellow oil. MS: 232 (M+1). Calc'd. for C14H21N3—231.34.

1. customthe mixture was bubbled with N2 for 10 min
2. addition10% Pd/C (200 mg) was added
3. filtrationThe mixture was filtered through Celite®
4. concentrationconcentrated in vacuo
5. customto afford a light yellow oil