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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2385699Generated: November 1, 2026

1-(2-Hydroxyethyl)piperazine → HCID 58203954, compound

https://huagongshe.com/reaction/2385699

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Hydroxyethyl)piperazineHCID 7677—
Reactant8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acidHCID 58203883—
ProductHCID 58203954HCID 58203954—

Reaction Steps

Following the procedure for 103, 8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid (50.0 mg, 0.2 mmol) was reacted with 2-(piperazin-1-yl)ethanol (1.2 equiv) to give 160 (20.9 mg, M+1 426.1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263633B2
Source datasetuspto-grants-2012_09
ORD IDord-39fa453d1bbc48bc8780dc0d43543b31
Source noteuspto-grants-2012_09