Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2385901Generated: October 31, 2026

8-Bromo-2-[2-(2,2,2-trifluoro-ethyl)-2H-[1,2,4]triazol-3-yl]-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene → HCID 58204253, compound

https://huagongshe.com/reaction/2385901

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Bromo-2-[2-(2,2,2-trifluoro-ethyl)-2H-[1,2,4]triazol-3-yl]-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azuleneHCID 58203849—
Reactant(S)-1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-2-olHCID 67050610—
ProductHCID 58204253HCID 58204253—

Reaction Steps

Following the procedure for 114, 8-Bromo-2-[2-(2,2,2-trifluoro-ethyl)-2H-[1,2,4]triazol-3-yl]-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene was reacted with (S)-1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-yl]-propan-2-ol to give 381. MS (ESI+) 477.1

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263633B2
Source datasetuspto-grants-2012_09
ORD IDord-87de5d8ccfd84daba609f89b385e9696
Source noteuspto-grants-2012_09