Methanesulfonyl chloride → 3,3,3-Trifluoropropyl methanesulfonate

HRID 2386204Notes

Reaction equation

[F:1][C:2]([F:7])([F:6])[CH2:3][CH2:4][OH:5].[CH3:8][S:9](Cl)(=[O:11])=[O:10]>>[CH3:8][S:9]([O:5][CH2:4][CH2:3][C:2]([F:7])([F:6])[F:1])(=[O:11])=[O:10]

Participants

Reactant 2

HCID 31297Methanesulfonyl chloride

HCID 1375123,3,3-Trifluoro-1-propanol

Product 1

HCID 252105013,3,3-Trifluoropropyl methanesulfonate

Procedure

3,3,3-Trifluoropropyl methanesulfonate was prepared by reaction of 3,3,3-trifluoropropanol with methanesulfonyl chloride by an analogous procedure to that used for Example 52 step 1.

Sources & evidence

ORD record: ord-85e709b0f7ba4f3693f9888530610eca
Source dataset: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08268823B2

Reaction notes

Loading…