HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichloropyrimidine → 3-(2-Chloro-pyrimidin-4-yl)-benzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichloropyrimidine | HCID 77531 | — |
| Reactant | (3-Ethoxycarbonylphenyl)boronic acid | HCID 3249312 | — |
| Product | 3-(2-Chloro-pyrimidin-4-yl)-benzoic acid ethyl ester | HCID 24901959 | — |
Reaction Steps
2,4 dichloropyrimidine was coupled to 3-carboethoxyphenylboronic acid following procedure A. LC-MS showed the product to be >95% pure and to have the expected M+H+ of 195.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08268822B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-04eef4a652b84d35bad28f8969fb12f6 |
| Source note | uspto-grants-2012_09 |