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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386359Generated: October 30, 2026

Methanesulfonyl chloride → N-[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-N-pyridin-2-ylmethyl-methanesulfonamide

https://huagongshe.com/reaction/2386359

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
ReactantHCID 86603248HCID 86603248—
ProductN-[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-N-pyridin-2-ylmethyl-methanesulfonamideHCID 86603247—

Reaction Steps

Intermediate 10 was coupled with methanesulfonyl chloride following procedure D. LC-MS showed the product had the expected M+H+ of 389.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268822B2
Source datasetuspto-grants-2012_09
ORD IDord-a0545dbc3dd448cd8d55d77e02da82e9
Source noteuspto-grants-2012_09