2-Pyridineethanamine → HCID 86603254, compound

HRID 2386365Notes

Reaction equation

HRID 2386365 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=2)[CH:11]=O)[CH:5]=[CH:4][N:3]=1.[N:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[CH2:22][CH2:23][NH2:24]>>[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:13]=[CH:14][CH:15]=2)[CH2:11][NH:24][CH2:23][CH2:22][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][N:16]=2)[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 759192-PyridineethanamineHCID 249019653-(2-Chloro-pyrimidin-4-yl)-benzaldehyde

Product 1

HCID 86603254HCID 86603254, compound

Procedure

Intermediate 1 was coupled with 2-pyridin-2-yl-ethylamine following procedure B. LC-MS showed the product had the expected M+H+ of 325.

Sources & evidence

ORD record
ord-4fadc177f5ac4024ab692869d251e465
Source dataset
uspto-grants-2012_09
Patent number
US08268822B2

Reaction notes

Loading…