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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2386371Generated: October 27, 2026

4-Pyridineethanamine → N-(3-(2-chloropyrimidin-4-yl)benzyl)-2-(pyridine-4-yl)ethanamine

https://huagongshe.com/reaction/2386371

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PyridineethanamineHCID 83275—
Reactant3-(2-Chloro-pyrimidin-4-yl)-benzaldehydeHCID 24901965—
ProductN-(3-(2-chloropyrimidin-4-yl)benzyl)-2-(pyridine-4-yl)ethanamineHCID 86603257—

Reaction Steps

Intermediate 1 was coupled with 2-pyridin-4-yl-ethylamine following procedure B. LC-MS showed the product had the expected M+H+ of 325.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08268822B2
Source datasetuspto-grants-2012_09
ORD IDord-4ee1a1b8e48f459397d457e1e8dffd68
Source noteuspto-grants-2012_09